// multi-utility computation suite · offline · instant · precise
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med.dissolution-Noyes-Whitney Calculator
Applies the Noyes-Whitney equation to calculate the dissolution rate of a solid drug from diffusion coefficient, surface area, and concentration gradient. Dissolution rate limits oral bioavailability for poorly soluble drugs — the foundation of pharmaceutical formulation science for BCS Class II and IV compounds.
Inputs
D Diffusivity Cm2 S
Reference formula or conversion factor shown for context.
A Surface Cm2
Two-dimensional surface extent (m²). For complex shapes, break into simpler sub-shapes and sum.
H Layer Cm
Perpendicular measurement through the material. For insulation: thicker is better. For beams: directly affects bending resistance.
Cs Mg Ml
Reference formula or conversion factor shown for context.
C Bulk Mg Ml
Amount of solute per unit volume. Higher concentration = more solute dissolved.
Results
dissolution rate dM/dt (mg/s)
The value at the specified point or condition.
dissolution rate (mg/min)
The value at the specified point or condition.
driving force (Cs-C) (mg/mL)
Sample size or count used in the calculation.
dM/dt = D·A/h·(Cs-C)
Reference formula or conversion factor shown for context.
BCS classification link
Category assigned based on where the computed value falls on a defined scale. Check which standard or guideline defines these boundaries.