// multi-utility computation suite · offline · instant · precise
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health.medication-half-life-dosing Calculator
Calculates the dosing interval and maintenance dose required to maintain plasma concentration between minimum and maximum target levels. The dosing interval in multiples of the half-life determines the peak-to-trough ratio — narrow intervals produce less fluctuation but higher trough levels.
Inputs
Half Life Hr
Reference formula or conversion factor shown for context.
Target Trough Mg L
Amount of solute per unit volume. Higher concentration = more solute dissolved.
Target Peak Mg L
Amount of solute per unit volume. Higher concentration = more solute dissolved.
Volume Distribution L
Three-dimensional space occupied (m³ or L). 1 m³ = 1,000 L.
Results
dosing interval τ (hours)
The result expressed in hours. Divide by 24 to convert to days.
dose per interval (mg)
Sample size or count used in the calculation.
elimination rate ke (1/hr)
The value at the specified point or condition.
τ = -ln(Cmin/Cmax)/ke
Sample size or count used in the calculation.
dose = Vd × (Cpeak - Ctrough)
Reference formula or conversion factor shown for context.
clinical note
Supplementary information explaining an assumption, caveat, or important context for interpreting the result.