sci.membrane-potential-Goldman Calculator
Calculates membrane potential from the Goldman-Hodgkin-Katz equation accounting for multiple permeable ions: V_m = (RT/F) × ln[(ΣP_K[K⁺]_o + ΣP_Na[Na⁺]_o + ΣP_Cl[Cl⁻]_i)/(ΣP_K[K⁺]_i + ΣP_Na[Na⁺]_i + ΣP_Cl[Cl⁻]_o)]. Resting neuronal V_m ≈ −70 mV, set by K⁺ permeability dominance.
Inputs
- P K
- Reference formula or conversion factor shown for context.
- P Na
- Reference formula or conversion factor shown for context.
- P Cl
- Reference formula or conversion factor shown for context.
- K Out Mm
- Reference formula or conversion factor shown for context.
- K In Mm
- Reference formula or conversion factor shown for context.
- Na Out Mm
- Reference formula or conversion factor shown for context.
- Na In Mm
- Reference formula or conversion factor shown for context.
- Cl Out Mm
- Reference formula or conversion factor shown for context.
- Cl In Mm
- Reference formula or conversion factor shown for context.
- T K
- Thermal state of the substance. Check whether the formula needs Celsius, Fahrenheit, or Kelvin (K = °C + 273.15).
Results
- membrane potential Vm (mV)
- Sample size or count used in the calculation.
- Nernst potential E_K (mV)
- Sample size or count used in the calculation.
- Nernst potential E_Na (mV)
- Sample size or count used in the calculation.
- Goldman-Hodgkin-Katz equation (1943)
- The value at the specified point or condition.
- resting potential reference
- Sample size or count used in the calculation.
- permeability ratio
- The proportional relationship between two quantities.
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